FAQ - Frequently Asked Questions

This section describes the procedure for everyday startup when the vacuum system of the mass spectrometer has already been started up (the power is ON).

 

1. Turn ON the power to every unit of the LC.

 

2. Check that the nitrogen gas/dry air generator is turned on and supply nitrogen gas to the MS.
  Nitrogen gas supply pressure: 690 to 800 kPa, purity: 97 % or more. Dry air supply pressure: 690 to 800 kPa.

  LCMS-2050: Nitrogen gas supply pressure: 600 to 680 kPa, Purity: 90 % or higher*1, *2

    NOTE*1: Should not contain any organic matter (oil, hydrocarbons, etc.).
    NOTE*2: Note the following risks when using high-purity nitrogen gas (cylinder, liquid nitrogen, etc.):
      • Discharge in the ionization unit: Discharge may occur in the high voltage part. Ionization becomes unstablewhen a large discharge occurs, which may affect analysis results. When discharge is observed, use the nitrogen gas generator at a lower voltage.
      • Generation of foreign matter at the tip of the corona needle: When using a mobile phase with a high acetonitrile composition, carbon-derived polymer is generated at the tip of the corona needle, which may cause unstable sensitivity. To prevent polymer generation, clean the corona needle regularly.

 

3. Turn on the peripheral units (monitor, printer, etc.), turn on the power to the PC and start Windows.

 

4. Start up LabSolutions.

 

5. Open the valve of the CID gas cylinder if it is closed.
  In this case, click [Advanced], then click [Open] for [CID Gas valve].

 

 

6. Remove the DL plug if it is mounted.

 

7. Turn on the LC pump and oven, and the LCMS heated block, DL heater, interface heater, and gas, and start operation.

  NOTE: The pump cannot be turned ON when the nebulizer gas is OFF.
  The interface heater cannot be turned ON when the heating gas is OFF.