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Decrease in sensitivity (LCMS)
Decrease in sensitivity (LCMS)
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Answer
The following factors and solutions are possible.(Please check from the top)
0. Auto-Tuning. Click here for Points for Auto-Tuning necessity.
1. Replacing (Cleaning) the DL. Click here for How to check for DL problems.
2. Cleaning the Lens. Click here for How to check for lens problems.
3. Replacing the ESI Pipe. Click here for How to check for ESI Pipe problems.
4. Cleaning the Heater block and Sampling Cone. Click here for How to check for Heater block and Sampling Cone problems.
5. Cleaning inside the Probe Holder.
6. Cleaning the ESI Probe (Nozzle). Click here for How to check for ESI Probe and Nozzle problems.
7. Cleaning the Orifice. Click here for How to check for Orifice problems.
8. Replacing the PEEK Tube. Click here for How to check for ESI PEEK Tube problems.
9. Cleaning the LC Flow Line.
10. Adjusting the Probe Position. Click here for How to check for ESI Probe position problems.
11. Replacing the Mobile Phase/Bottle.
1. Replacing (Cleaning) the DL. Click here for How to check for DL problems.
2. Cleaning the Lens. Click here for How to check for lens problems.
3. Replacing the ESI Pipe. Click here for How to check for ESI Pipe problems.
4. Cleaning the Heater block and Sampling Cone. Click here for How to check for Heater block and Sampling Cone problems.
5. Cleaning inside the Probe Holder.
6. Cleaning the ESI Probe (Nozzle). Click here for How to check for ESI Probe and Nozzle problems.
7. Cleaning the Orifice. Click here for How to check for Orifice problems.
8. Replacing the PEEK Tube. Click here for How to check for ESI PEEK Tube problems.
9. Cleaning the LC Flow Line.
10. Adjusting the Probe Position. Click here for How to check for ESI Probe position problems.
11. Replacing the Mobile Phase/Bottle.
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