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No : 4633
Date of Issue : 2020/12/22 13:49
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HPLC: What solvent cannot be used?

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Products Search > HPLC > Common

Answer

• It is basically used within the pH described in the specifications of the instruction manual of each instruments.

• Not covered by warranty if used for purposes other than high performance liquid chromatograph.

• Instruments containing stainless steel in the liquid-contacting part materials;

Halogen ions can corrode the stainless steel material used in the plumbing, so avoid, as much as possible, mobile phases that contain halogen ions - such as KCI, NaCI and NH4CI - or mobile phases that generate halogen ions in certain reactions. If such mobile phases must be used, clean all flow lines thoroughly with distilled water immediately after analysis.

• When use PEEK piping, please see here (Click).

• When using THF, chloroform, DMF, or HFIP for GPC analysis, etc., options for each instruments are available.

Please contact a Shimadzu sales or service representative.

• The following solvents cannot be used with DGU-20/40.

• HFIP (hexafluoroisopropanol)
• Hydrogen fluoride
• 1,1,2-Trichloro-1,2,2-trifluoroethane
• Fluorinert™ Electronic Liquids FC-40
• Fluorinert™ Electronic Liquids FC-72
• Fluorinert™ Electronic Liquids FC-75
• Perfluoro benzene
• Perfluoro octane
• Perfluoro decalin
• Perfluoro 1-methyldecalin
• Perfluoro dimethyldecalin
• Perfluoro methyl-cyclohexane
• Perfluoro dimethyl-cyclohexane
• AK-225
• Other fluorinated solvents
• Nitric acid having a concentration of 30% min.
• Hydrogen peroxide

CAUTION: When solvents with high volatility and solubility (hexane, heptane, THF, ethyl acetate etc.) are used, replace the channel inside the instrument with isopropyl alcohol (IPA) and stop operation.

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