FAQ - Frequently Asked Questions
Selecting a (MR) Mixer
Selecting a (MR) Mixer
- Category :
Answer
Baseline stability is dependent on the flowrate, detector, and mobile phase. Therefore, select a mixer that is appropriate for given system configuration and analytical conditions.
| Gradient Type | Mixer |
| High-Pressure Gradient | MR 180 μL |
| Low-Pressure Gradient | MR 300 μL LPGE (To reduce system volume, use a MR 40 μL LPGE mixer.) |
The table below shows an example of a mixer used to reduce the gradient delay volume in a high-pressure gradient system, such as for ultra high-speed analysis.
It indicates the smallest capacity mixer usable for the given combination of detector and mobile phase.
It indicates the smallest capacity mixer usable for the given combination of detector and mobile phase.
| Using a Mobile Phase Containing Trifluoroacetic Acid | Using a Mobile Phase Containing Formic or Acetic Acids | Using a Mobile Phase with Low Absorption, such as Water (Including Buffer Solutions), Organic Solvents, or Mixtures Thereof | |
| Using a Photodiode Array Detector | MR 180 μL | MR 180 μL | MR 180 μL |
| Using an Absorbance Detector | MR 180 μL | MR 100 μL | MR 40 μL |
| Using LCMS or LCMSMS | - | MR 20 μL | MR 20 μL |
If multiple detectors are connected, use the mixer with the largest capacity. For example, if using LC/MS and PDA detectors, use the MR180 μLII. If the type of mobile phase to be used is unknown, use the largest capacity mixer, which is the MR180 μLII.
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